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Presentation of a central venous catheter misplacement case

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Placement was performed under ultrasound guidance, with confirmation of the wire within the venous lumen. Radiographs suggested that the introducer had perforated the innominate vein. Contrast was injected through the single-lumen infusion catheter and showed cannulation of the left internal mammary vein” Tashjian et al 92019). Abstract: We present a central venous catheter misplacement case. […]

Peripheral intravenous access for extracorporal photopheresis

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Extracorporal photopheresis (ECP) was shown to be effective without severe side effects in the treatment of cutaneous T cell lymphoma (CTCL) and graft versus host disease (GvHD). However, only few studies investigated the practical aspects of ECP” Hambsch et al (2019). Abstract: BACKGROUND: Extracorporal photopheresis (ECP) was shown to be effective without severe side effects […]

Treatment of cancer-related venous thromboembolism

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Cancer patients develop a hypercoagulable state with a four- to seven-fold higher thromboembolic risk compared to non-cancer patients” Grandoni and Alberio (2019). Abstract: Cancer patients develop a hypercoagulable state with a four- to seven-fold higher thromboembolic risk compared to non-cancer patients. Thromboembolic events can precede the diagnosis of cancer, but they more often occur at […]

Financial impact of approaches to reduce bacterial contamination of platelet transfusions

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Bacterial contamination of platelets remains the leading infectious risk from blood transfusion. Pathogen reduction (PR), point-of-release testing (PORt), and secondary bacterial culture (SBC) have been proposed as alternative risk control strategies, but a comprehensive financial comparison has not been conducted” Kacker et al (2019). Abstract: BACKGROUND: Bacterial contamination of platelets remains the leading infectious risk […]

Continuous etomidate infusion for the management of severe Cushing syndrome

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Demonstrate the safety and efficacy of a standardized intravenous etomidate infusion protocol in normalizing cortisol levels in patients with severe and life-threatening hypercortisolism” Carroll et al (2019). Abstract: OBJECTIVE: Demonstrate the safety and efficacy of a standardized intravenous etomidate infusion protocol in normalizing cortisol levels in patients with severe and life-threatening hypercortisolism. METHODS: A retrospective […]

Using Lean methodology to reduce infusion pump errors

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Since previous attempts to reduce medication errors with infusion pumps failed in our intensive care unit, we chose the Lean approach to accomplish a 50% reduction of administration errors in 6 months. Besides improving quality of care and patient safety, we wanted to determine the effectiveness of Lean in healthcare” van der Sluijs et al (2019). […]

End of life palliative sedation via intraosseous vascular access

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No complications were noted from this route of administration. We advocate the use of IO access in the palliative care of terminal ill patients when a venous cannulation is not possible” Mansfeld et al (2019). Abstract: Intraosseous (IO) access is normally reserved for emergencies and critical care conditions when venous cannulation is not possible. Nonetheless, […]

Contamination of health care personnel during removal of contaminated gloves

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In simulations of contaminated glove removal, 37% of health care personnel using their typical doffing technique contaminated their skin with a fluorescent solution” Alhmidi et al (2019). Reference: In simulations of contaminated glove removal, 37% of health care personnel using their typical doffing technique contaminated their skin with a fluorescent solution. The frequency of contamination […]

Review of the dosing and monitoring of vancomycin

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We have evaluated the literature to review optimal dosing and monitoring of intravenous vancomycin in adults, in response to evolving understanding of targets associated with efficacy and toxicity” Drennan et al (2018). Abstract: We have evaluated the literature to review optimal dosing and monitoring of intravenous vancomycin in adults, in response to evolving understanding of […]

Review of the safety of intravenous drug delivery systems

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The purpose of this conference was to evaluate the safety of intravenous (IV) infusion systems used for medication administration” Rodriguez (2018). Abstract: This review was prepared in advance of the Third Consensus Development Conference on the Safety of Intravenous Drug Delivery Systems that was held at the W Hotel in Chicago, Illinois, from November 1 […]